New amide bond ligation method described in JACS

Jan 18th, 14:51

Arun Shivalingam, Agnes Tyburn and Afaf El-Sagheer’s paper Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation, which describes an exciting new amide bond ligation method for DNA that is chemically orthogonal to CuAAC “click” ligation, has been published online in J. Amer. Chem. Soc..