High-information addressable DNA nanostructures

J. Tumpane, P. Sandin, R. Kumar, V. E. C. Powers, P. Lincoln, B. Albinsson, L. M. Wilhelmsson, T. Brown and B. Nordn. Biophys. J. 47A-47A, 2007.

Abstract

The inherent self-assembly properties of DNA make it ideal in nanotechnology. We present a fully addressable DNA nanostructure with the smallest possible unit cell, a hexagon with a side-length of only 3.4 nm.(2,3) Using novel three-way oligonucleotides, where each side has a unique double-stranded DNA sequence that can be assigned a specific address, we will build a non-repetitive two-dimensional grid.