Dr Nittaya Gale

Dr Nittaya Gale

Nittaya carried out research her PhD in Prof. Jeremy Kilburn’s group, then moved to Southampton Polypeptides, before returning to Southampton University to take up a post-doctoral position in Dr Iris Nandakumar’s Nanotechnology research group. She joined the Brown group as a post-doctoral researcher in 2005 where she developed a new rapid method for human forensic DNA analysis which has since been patented and commercialized by LGC. Nittaya moved to ATDBio, where she continued to collaborate with Prof. Brown.

20 Papers

HyBeacon probes for rapid DNA sequence detection and allele discrimination

D. J. French, D. G. McDowell, P. Debenham, N. Gale and T. Brown. Methods Mol. Biol. 2006.

Triplex addressability as a basis for functional DNA nanostructures

J. Tumpane, R. Kumar, E. P. Lundberg, P. Sandin, N. Gale, I. S. Nandhakumar, B. Albinsson, P. Lincoln, L. M. Wilhelmsson, T. Brown and B. Norden. Nano Lett. 7 (12), 3832-3839, 2007.

Addressable high-information-density DNA nanostructures

J. Tumpane, P. Sandin, R. Kumar, V. E. C. Powers, E. P. Lundberg, N. Gale, P. Baglioni, J. M. Lehn, B. Albinsson, P. Lincoln, L. M. Wilhelmsson, T. Brown and B. Norden. Chem. Phys. Lett. 440 (1), 125-129, 2007.

A Raman probe for selective wrapping of single-walled carbon nanotubes by DNA

Q. H. Yang, N. Gale, C. J. Oton, F. Li, A. Vaughan, R. Saito, I. S. Nandhakumar, Z. Y. Tang, H. M. Cheng, T. Brown and W. H. Loh. Nanotechnology 18 (40), 1-5, 2007.

Deuterated water as super solvent for short carbon nanotubes wrapped by DNA

Q. H. Yang, N. Gale, C. J. Oton, H. Li, I. S. Nandhakumar, Z. Y. Tang, T. Brown and W. H. Loh. Carbon 45 (13), 2701-2703, 2007.

Interrogation of short tandem repeats using fluorescent probes and melting curve analysis: A step towards rapid DNA identity screening

D. J. French, R. L. Howard, N. Gale, T. Brown, D. G. McDowell and P. G. Debenham. Forensic Sci. Int. Genet. 2 (4), 333-339, 2008.

Rapid typing of STRs in the human genome by HyBeacon (R) melting

N. Gale, D. J. French, R. L. Howard, D. G. McDowell, P. G. Debenham and T. Brown. Org. Biomol. Chem. 6 (24), 4553-4559, 2008.

Loosening the DNA wrapping around single-walled carbon nanotubes by increasing the strand length

Q. H. Yang, Q. Wang, N. Gale, C. J. Oton, L. Cui, I. S. Nandhakumar, Z. Zhu, Z. Tang, T. Brown and W. H. Loh. Nanotechnology 20 (19), 195603, 2009.

Analysis of Short Tandem Repeats by Using SERS Monitoring and Electrochemical Melting

D. K. Corrigan, N. Gale, T. Brown and P. N. Bartlett. Angew. Chem. Int. Ed. 49 (34), 5917-5920, 2010.

Peptide nucleic acid probes with charged photocleavable mass markers: Towards PNA-based MALDI-TOF MS genetic analysis

R. J. Ball, P. S. Green, N. Gale, G. J. Langley and T. Brown. Artificial DNA: PNA & XNA 1 (1), 27-35, 2010.

2’-Substituted 2-Amino-3-Methylpyridine Ribonucleosides in Triplex-Forming Oligonucleotides: Triplex Stability is Determined by Chemical Environment

C. Lou, Q. Xiao, R. R. Tailor, N. Ben Gaied, N. Gale, M. E. Light, K. R. Fox and T. Brown. Med. Chem. Comm. 2, 550-558, 2011.

PNA HyBeacons for analysis of human mutations related to statin-induced myopathy

N. Gale, P. Kocalka, C. Mardle and T. Brown. Artificial DNA: PNA & XNA 2 (3), 1-11, 2011.

Self reporting RNA probes as an alternative to cleavable small molecule mass tags

J. Riley, T. Brown, N. Gale, J. Herniman and G. J. Langley. Analyst 137, 5817-5822, 2012.

Denaturation of dsDNA Immobilised at a Negatively Charged Gold Electrode is not caused by Electrostatic Repulsion

R. P. Johnson, N. Gale, J. A. Richardson, T. Brown and P. N. Bartlett. Chem. Sci. 4, 1625-1632, 2013.

The Structure of FemXWv in Complex with a Peptidyl-RNA Conjugate: Mechanism of Aminoacyl Transfer from Ala-tRNAAla to Peptidoglycan Precursors

M. Fonvielle, I. Li de La Sierra-Gallay, A. H. El-Sagheer, M. Lecerf, D. Patin, D. Mellal, C. Mayer, D. Blanot, N. Gale, T. Brown, H. van Tilbeurgh, M. Ethève-Quelquejeu and M. Arthur. Angew. Chem. Int. Ed. 52 (28), 7278-7281, 2013.

Self-reporting hybridisation assay for miRNA analysis

J. Riley, T. Brown, N. Gale, J. Herniman and G. J. Langley. Analyst 139, 1088-1092, 2014.

Using Surface-Enhanced Raman Spectroscopy and Electrochemically Driven Melting to Discriminate Yersinia pestis from Y. pseudotuberculosis Based on Single Nucleotide Polymorphisms within Unpurified Polymerase Chain Reaction Amplicons

E. Papadopoulou, S. A. Goodchild, D. W. Cleary, S. A. Weller, N. Gale, M. R. Stubberfield, T. Brown and P. N. Bartlett. Anal. Chem. 87 (3), 1605-1612, 2015.

Strain discrimination of Yersinia pestis using a SERS-based electrochemically driven melting curve analysis of variable number tandem repeat sequences

E. Papadopoulou, N. Gale, S. A. Goodchild, D. W. Cleary, S. A. Weller, T. Brown and P. N. Bartlett. Chem. Sci. 2015.

Reversible Energy-Transfer Switching on a DNA Scaffold

M. Bälter, M. Hammarson, P. Remón, S. Li, N. Gale, T. Brown and J. Andréasson. J. Am. Chem. Soc. 137 (7), 2444-2447, 2015.

Specifically horizontally tethered DNA probes on Au surfaces allow labelled and label-free DNA detection using SERS and electrochemically driven melting

E. Papadopoulou, N. Gale, J. F. Thompson, T. A. Fleming, T. Brown and P. N. Bartlett. Chem. Sci. 7 (1), 386-393, 2016.