Our research is interdisciplinary, focusing on nucleic acid chemistry and its applications in other fields including DNA diagnostics, forensic science and nanotechnology.
Over 350 research papers and patents
Our publications have been cited more than 14000 times.
Our research has led to the foundation of three companies, as well as the development of several new technologies in collaboration with industrial partners.
5-Formylcytosine shown not to change the global structure of DNA
In a paper published in Nat. Struct. Mol. Biol., we have shown that, contrary to previous observations, 5-formylcytosine does not significantly alter DNA structure
RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks