New Technologies for DNA analysis-A review of the READNA Project

S. McGinn, D. Bauer, T. Brefort, L. Dong, A. H. El-Sagheer, A. Elsharawy, G. Evans, E. Falk-Sorqvist, M. Forster, S. Fredriksson, P. Freeman, C. Freitag, J. Fritzsche, S. Gibson, M. Gullberg, M. Gut, S. Heath, I. Heath-Brun, A. J. Heron, J. Hohlbein, R. Ke, O. Lancaster, L. Le Reste, G. Maglia, R. Marie, F. Mauger, F. Mertes, M. Mignardi, L. Moens, J. Oostmeijer, R. Out, J. N. Pedersen, F. Persson, V. Picaud, D. Rotem, N. Schracke, J. Sengenes, P. F. Stahler, B. Stade, D. Stoddart, X. Teng, C. D. Veal, N. Zahra, H. Bayley, M. Beier, T. Brown, C. Dekker, B. Ekstrom, H. Flyvbjerg, A. Franke, S. Guenther, A. N. Kapanidis, J. Kaye, A. Kristensen, H. Lehrach, J. Mangion, S. Sauer, E. Schyns, J. Tost, J. M. L. M. van Helvoort, P. J. van der Zaag, J. O. Tegenfeldt, A. J. Brookes, K. Mir, M. Nilsson, S. Willcocks and I. G. Gut. N. Biotechnol. 33 (3), 311-330, 2016.


The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 4 1/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and developed a huge body of insights into nucleic acid analysis, ranging from improvements and implementation of current technologies to the most promising sequencing technologies that constitute a 3(rd) and 4(th) generation of sequencing methods with nanopores and in situ sequencing, respectively.