Second PNAS paper in two years!
Jun 30th 2011, 08:27
The paper Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli, published in PNAS this week, is the second paper published by the Brown group in the journal PNAS in two years. The paper, written by Afaf El-Sagheer, Pia Sanzone (a student in the Ali Tavassoli group at Southampton), Rachel Gao, Ali Tavassoli and Tom Brown, describes how DNA containing an artificial triazole linkages (in the place of a DNA phosphodiester linkage) was copied during PCR with high fidelity and a gene containing the triazole linker was functional in Escherichia coli.