New improved Cy3 analogues
Apr 18th 2012, 08:15
Cy3B has long been known to be an extremely bright and stable fluorescent dye (with a much higher quantum yield than other cyanine dyes), but has only been available as a post-synthetic label, limiting its use. In a paper published in Nucleic Acids Res., we demonstrate the first synthesis of Cy3B phosphoramidite monomers for solid-phase oligo synthesis.