2'-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices

L. Brennan, G. M. Peng, N. Srinivasan, K. R. Fox and T. Brown. Nucleosides Nucleotides Nucl. Acids 26 (10-12), 1283-1286, 2007.

Abstract

The nucleoside analogues 2'-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucleotides. Their triplex-stabilising properties have been determined in fluorescence melting experiments.