High-information addressable DNA nanostructures

J. Tumpane, P. Sandin, R. Kumar, V. E. C. Powers, P. Lincoln, B. Albinsson, L. M. Wilhelmsson, T. Brown and B. Norden. 51st Annual Meeting of the Biophysical-Society, Baltimore 47A, 2007.


The inherent self-assembly properties of DNA make it ideal in nanotechnology. We present a fully addressable DNA nanostructure with the smallest possible unit cell, a hexagon with a side-length of only 3.4 nm.(2,3) Using novel three-way oligonucleotides, where each side has a unique double-stranded DNA sequence that can be assigned a specific address, we will build a non-repetitive two-dimensional grid.