Analysis of Short Tandem Repeats by Using SERS Monitoring and Electrochemical Melting

D. K. Corrigan, N. Gale, T. Brown and P. N. Bartlett. Angew. Chem. Int. Ed. 49 (34), 5917-5920, 2010.


Electrochemical melting with SERS detection on nanostructured electrodes was utilized to discriminate between DNA sequences with different numbers of the GATA short tandem repeat sequence. The technique has unique advantages for incorporation into a field-operable DNA analysis device.