Six-Colour HyBeacon Probes for Multiplex Genetic Analysis

J. A. Richardson, M. Gerowska, M. Shelbourne, D. J. French and T. Brown. ChemBioChem 11 (18), 2530-2533, 2010.


A combination of six HyBeacon probes has been used in multiplex genetic analysis to analyse mutations in the CFTR gene of PCR-amplified human DNA. Multicolour HyBeacons of this type have great potential in human genetic screening and point-of-care diagnosis.