New two dimensional liquid-phase colorimetric assay based on old iodine-starch complexation for simple, low-cost, portable, naked-eye detection and quantification of analytes

J. Nie, T. Brown and Y. Zhang. Chem. Commun. 2016.


A new class of quantitative point-of-care liquid-phase colorimetric assay (LPCA) termed as two dimensional (2D) LPCA is designed using old iodine-starch complexation reaction firstly discovered in 1814. The naked-eye 2D LPCA’s utility is well demonstrated with simple, low-cost, portable detection and quantification of model analytes in buffer or/and human serum samples without the use of external electronic readers.