Paper on copper-free click ligation published in ChemComm

May 6th 2011, 12:22

The paper ‘Fast copper-free click DNA ligation by the ring-strain promoted alkyne-azide cycloaddition reaction’ has been published online in ChemComm. The communication describes the fast (< 1 min) ligation of DNA strands in an alkyne–azide [3+2] cycloaddition reaction, in the absence of copper.