In a paper published in Nat. Struct. Mol. Biol., we have shown that, contrary to previous observations, 5-formylcytosine does not significantly alter DNA structure
Arun Shivalingam, Agnes Tyburn and Afaf El-Sagheer’s paper Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation, which describes an exciting new amide bond ligation method for DNA that is chemically orthogonal to CuAAC “click” ligation, has been published online in J. Amer. Chem. Soc..
Prof. Tom Brown is the overall winner in the BBSRC Innovator of the Year 2016, for his work on Extending the Boundaries of Nucleic Acid Chemistry. The award was announced today at the BBSRC Fostering Innovation event in London.