97 Papers found

< Showing 1 to 20

This year Last year Last 5 years Important papers Reviews All papers

Search

Chemically modified nucleic acids and DNA intercalators as tools for nanoparticle assembly

Angela F. De Fazio, Doxi Misatziou, Ysobel R. Baker, Otto L. Muskens, Tom Brown and Antonios G. Kanaras. Chemical Society Reviews 50, 13410-13440, 2021.

Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors

Shifali Shishodia, Marina Demetriades, Dong Zhang, Nok Yin Tam, Pratheesh Maheswaran, Caitlin Clunie-O’Connor, Anthony Tumber, Ivanhoe K. H. Leung, Yi Min Ng, Thomas M. Leissing, Afaf H. El-Sagheer, Eidarus Salah, Tom Brown, Wei Shen Aik*, Michael A. McDonough*, and Christopher J. Schofield*. Journal of Medical Chemistry 64 (22), 16609-16625, 2021.

A New 1,5-Disubstituted Triazole DNA Backbone Mimic with Enhanced Polymerase Compatibility

Sven Epple, Aman Modi, Ysobel R. Baker, Ewa Wegrzyn, Diallo Traoré, Przemyslaw Wanat, Agnes E. S. Tyburn, Arun Shivalingam, Lapatrada Taemaitree, Afaf H. El-Sagheer, and Tom Brown*. Journal of the American Chemical Society 143 (39), 16293-16301, 2021.

Expanding the chemical functionality of DNA nanomaterials generated by rolling circle amplification

Ysobel R Baker, Liyiwen Yuan, Jinfeng Chen, Roman Belle, Robert Carlisle, Afaf H El-Sagheer, Tom Brown. Nucleic Acids Res. 49 (16), 9042-9052, 2021.

Artificial nucleic acid backbones and their applications in therapeutics, synthetic biology and biotechnology

Sven Epple, Afaf H. El-Sagheer, Tom Brown. Energing topics in life science 5 (5), 691-697, 2021.

Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq

Martin Philpott, Jonathan Watson, Anjan Thakurta, Tom Brown Jr, Tom Brown Sr, Udo Oppermann & Adam P. Cribbs. Nature Biotechnology 39, 1517-1520, 2021.

Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq

Philpott M, Watson J, Thakurta A, Brown T, Brown T, Oppermann U, Cribbs AP. Nature Biotechnology 39 (12), 1517-1520, 2021.

DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second

Alisina Bazrafshan, Maria-Eleni Kyriazi, Brandon Alexander Holt, Wenxiao Deng, Selma Piranej, Hanquan Su, Yuesong Hu, Afaf H. El-Sagheer, Tom Brown, Gabriel A. Kwong, Antonios G. Kanaras, and Khalid Salaita*. ACS Nano 15 (5), 8427-8438, 2021.

Mismatch detection in homologous strand exchange amplified by hydrophobic effects

Bengt Nordén, Tom Brown, Bobo Feng. Biopolymers 112 (4), 2021.

Enrichment of Skeletal Stem Cells from Human Bone Marrow Using Spherical Nucleic Acids

Miguel Xavier, Maria-Eleni Kyriazi, Stuart Lanham, Konstantina Alexaki, Elloise Matthews, Afaf H. El-Sagheer, Tom Brown, Antonios G. Kanaras*, and Richard O. C. Oreffo*. ACS Nano 15 (4), 6909-6916, 2021.

INSIGHT: A population-scale COVID-19 testing strategy combining point-of-care diagnosis with centralized high-throughput sequencing

Qianxin Wu, Chengqu Suo, Tom Brown, Tengyao Wang, Sarah A. Teichmann, Andrew R. Bassett. Science advances 7 (7), 2021.

DNA-Targeted Metallodrugs: An Untapped Source of Artificial Gene Editing Technology

Nicolò Zuin Fantoni, Tom Brown, Andrew Kellett. ChemBioChem 22 (13), 2184-2205, 2021.

A DNA sensor based on upconversion nanoparticles and two-dimensional dichalcogenide materials

Konstantina Alexaki, Davide Giust, Maria-Eleni Kyriazi, Afaf H. El-Sagheer, Tom Brown, Otto L. Muskens & Antonios G. Kanaras. Frontiers of Chemical Science and Engineering 15, 935-943, 2021.

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale

Damien J. Downes, Robert A. Beagrie, Matthew E. Gosden, Jelena Telenius, Stephanie J. Carpenter, Lea Nussbaum, Sara De Ornellas, Martin Sergeant, Chris Q. Eijsbouts, Ron Schwessinger, Jon Kerry, Nigel Roberts, Arun Shivalingam, Afaf El-Sagheer, A. Marieke Oudelaar, Tom Brown, Veronica J. Buckle, James O. J. Davies & Jim R. Hughes. Nature Communications 12, 531, 2021.

A Hitchhiker’s Guide to Click-Chemistry with Nucleic Acids

Nicolò Zuin Fantoni, Afaf H. El-Sagheer, and Tom Brown*. Chemical Reviews 121 (12), 7122-7154, 2021.

Strict conformational demands of RNA cleavage in bulge-loops created by peptidyl-oligonucleotide conjugates

Yaroslav Staroseletz, Bahareh Amirloo, Aled Williams, Alexander Lomzov, Kepa K Burusco, David J Clarke, Tom Brown, Marina A Zenkova, Elena V Bichenkova. Nucleic Acids Res. 48 (19), 10662-10679, 2020.

An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells

Martin R. Gill, Michael G. Walker, Sarah Able, Ole Tietz, Abirami Lakshminarayanan, Rachel Anderson, Rod Chalk, Afaf H. El-Sagheer, Tom Brown, Jim A. Thomas and Katherine A. Vallis. Chemical Science 11, 8936-8944, 2020.

Development of Gene-Targeted Polypyridyl Triplex-Forming Oligonucleotide Hybrids

Nicolò Zuin Fantoni, Bríonna McGorman, Zara Molphy, Daniel Singleton, Sarah Walsh, Afaf H. El-Sagheer, Vickie McKee, Tom Brown, Andrew Kellett. ChemBioChem 21 (24), 3563-3574, 2020.

Melting temperature measurement and mesoscopic evaluation of single, double and triple DNA mismatches

Luciana M. Oliveira, Adam S. Long, Tom Brown, Keith R. Fox and Gerald Weber. Chemical Science 11, 8273-8287, 2020.

Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor

Anna Wypijewska del Nogal, Anders F Füchtbauer, Mattias Bood, Jesper R Nilsson, Moa S Wranne, Sangamesh Sarangamath, Pauline Pfeiffer, Vinoth Sundar Rajan, Afaf H El-Sagheer, Anders Dahlén, Tom Brown, Morten Grøtli, L Marcus Wilhelmsson. Nucleic Acids Res. 48 (14), 7640-7652, 2020.

Showing papers 1-20 of 97 total (Page 1 of 5)

< Previous | 1 | 2 | 3 | 4 | 5 |