Reverse transcription of a triazole linkage in RNA has implications for RNA sequencing

Jun 3rd 2014, 11:54

In a paper published in ChemComm, we show that a bulky triazole linkage formed by a click reaction between 3’-azide and 5’-cyclooctyne oligonucleotides is read through by reverse transcriptase, with potential applications in RNA isolation, amplification and sequencing.

Prof. Tom Brown voted Chemistry World Entrepeneur of the Year

Jun 2nd 2014, 15:45

Prof. Tom Brown has been voted Chemistry World’s Entrepreneur of the Year for 2014. http://www.rsc.org/chemistryworld/2014/05/entrepreneur-2014-tom-brown

Click-linked DNA in human cells published in Angewandte Chemie

Jan 23rd 2014, 15:24

Our paper in collaboration with Ali Tavassoli (University of Southampton) entitled Transcription of Click-Linked DNA in Human Cells has been published online in Angewandte Chemie.

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