Click triazole linkage is fully biocompatible in E. coli
Aug 17th 2012, 14:36
A paper published this week in Nucleic Acids Res., in collaboration with Ali Tavassoli, demonstrates the full biocompatibility of a click DNA-backbone linker in a non-essential gene (the mCherry gene in E. coli). The results hint at the possibility of a fully synthetic approach to gene synthesis.
Copper-free DNA crosslinking
Aug 17th 2012, 14:26
A new method for DNA crosslinking and multiple orthogonal labelling is described in a paper published this week in ChemComm.
New SERS paper published
Aug 17th 2012, 14:18
A new SERS-based assay has been developed, for the detection of DNA hybridization and mutations. The method is described in a paper published recently in JACS, in collaboration with Prof. Phil Bartlett.