20th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
Prof. Tom Brown will speak at the XX International Roundtable on Nucleosides, Nucleotides and Nucleic Acids in Montreal, Canada, from 5-9 August 2012. Further details can be found at http://www.is3na.org/IS3NA_Society_Events.asp
New improved Cy3 analogues
Cy3B has long been known to be an extremely bright and stable fluorescent dye (with a much higher quantum yield than other cyanine dyes), but has only been available as a post-synthetic label, limiting its use. In a paper published in Nucleic Acids Res., we demonstrate the first synthesis of Cy3B phosphoramidite monomers for solid-phase oligo synthesis.
DNA triplexes in nanotechnology
In a paper published in ACS Nano in collaboration with Prof. Keith Fox, applications of the triplex approach to DNA recognition have been demonstrated in the synthesis of nanostructures.