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Selectivity and affinity of triplex-forming oligonucleotides containing 2'-aminoethoxy-5-(3-aminoprop-1-ynyl)uridine for recognizing AT base pairs in duplex DNA

S. D. Osborne, V. E. C. Powers, D. A. Rusling, O. Lack, K. R. Fox and T. Brown. Nucleic Acids Res. 32 (15), 4439-4447, 2004.

DNA sequence recognition by an isopropyl substituted thiazole polyamide

P. L. James, E. E. Merkina, A. I. Khalaf, C. J. Suckling, R. D. Waigh, T. Brown and K. R. Fox. Nucleic Acids Res. 32 (11), 3410-3417, 2004.

Effects of a hairpin polyamide on DNA melting: comparison with distamycin and Hoechst 33258

P. L. James, L. Le Strat, U. Ellervik, C. Bratwall, B. Norden, T. Brown and K. R. Fox. Biophys. Chem. 111 (3), 205-212, 2004.

DNA adopts normal B-form upon incorporation of highly fluorescent DNA base analogue tC: NMR structure and UV-Vis spectroscopy characterization

K. C. Engman, P. Sandin, S. Osborne, T. Brown, M. Billeter, P. Lincoln, B. Norden, B. Albinsson and L. M. Wilhelmsson. Nucleic Acids Res. 32 (17), 5087-5095, 2004.

MLPA-based point mutation analysis of the FBN1 gene in Marfan syndrome patients

D. J. Bunyan, T. Brown, R. Wycherley, J. Score, J. F. Harvey and N. C. P. Cross. British Human Genetics Conference, York S75-S75, 2004.

MLPA-based point mutation analysis of the FBN1 gene in Marfan syndrome patients

D. J. Bunyan, T. Brown, R. Wycherley, J. Score, J. F. Harvey and N. C. P. Cross. J. Med. Genet. 41, S75-S75, 2004.

An analogue of adenine that forms an A.T base pair of comparable stability to G.C

J. Booth, W. J. Cummins and T. Brown. Chem. Commun. 2208-2209, 2004.

Chemical modification and micropatterning of Si(100) with oligonucleotides

H. B. Yin, T. Brown, R. Greef, J. S. Wilkinson and T. Melvin. 29th International Conference on Micro and Nano Engineering (MNE 2003), Cambridge, England 830-836, 2003.

Sequence-selective metalation of double-helical oligodeoxyribonucleotides with Pt-II, Mn-II, and Zn-II ions

J. Vinje, J. A. Parkinson, P. J. Sadler, T. Brown and E. Sletten. Chem. Eur. J. 9 (7), 1620-1630, 2003.

Synthesis of fluorophore and quencher monomers for use in Scorpion primers and nucleic acid structural probes

C. M. McKeen, L. J. Brown, J. T. G. Nicol, J. M. Mellor and T. Brown. Org. Biomol. Chem. 1 (13), 2267-2275, 2003.

A new dark quencher for use in genetic analysis

J. P. May, L. J. Brown, I. Rudloff and T. Brown. Chem. Commun. 970-971, 2003.

DNA sequence specificity of triplex-binding ligands

M. D. Keppler, P. L. James, S. Neidle, T. Brown and K. R. Fox. Eur. J. Biochem. 270 (24), 4982-4992, 2003.

Thermodynamic and kinetic stability of intermolecular triple helices containing different proportions of C+.GC and T.AT triplets

P. L. James, T. Brown and K. R. Fox. Nucleic Acids Res. 31 (19), 5598-5606, 2003.

The solution structure of a DNA.RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications

J. I. Gyi, D. Q. Gao, G. L. Conn, J. O. Trent, T. Brown and A. N. Lane. Nucleic Acids Res. 31 (10), 2683-2693, 2003.

Synthesis of HyBeacons and dual-labelled probes containing 2'- fluorescent groups for use in genetic analysis

N. Dobson, D. G. McDowell, D. J. French, L. J. Brown, J. M. Mellor and T. Brown. Chem. Commun. 1234-1235, 2003.

Crystal structure of the Escherichia coli DCM very-short-patch DNA repair endonuclease bound to its reaction product-site in a DNA superhelix

K. A. Bunting, S. M. Roe, A. Headley, T. Brown, R. Savva and L. H. Pearl. Nucleic Acids Res. 31 (6), 1633-1639, 2003.

Cleavage of fragments containing DNA mismatches by enzymic and chemical probes

J. Brown, T. Brown and K. R. Fox. Biochem. J 371, 697-708, 2003.

Novel photocleavable universal support for oligonueleotide synthesis

E. Anderson, T. Brown and D. Picken. Nucleosides Nucleotides Nucl. Acids 22 (5-8), 1403-1406, 2003.

First synthesis of 1-deazacytidine, the C-nucleoside analogue of cytidine

M. Sollogoub, K. R. Fox, V. E. C. Powers and T. Brown. Tetrahedron Lett. 43 (17), 3121-3123, 2002.

Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U

M. Sollogoub, R. A. J. Darby, B. Cuenoud, T. Brown and K. R. Fox. Biochemistry 41 (23), 7224-7231, 2002.

Showing papers 281-300 of 428 total (Page 15 of 22)

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