Prof. Graeme Conn

Prof. Graeme Conn

Graduate student (1992-1996)

A former PhD student in the Brown group, Graeme has been a successful researcher in the UK, before being head-hunted as Associate Professor of Biochemistry by Emory University in the USA.

9 Papers

Hydration of the RNA duplex r(CGCAAAUUUGCG)2 determined by NMR

M. R. Conte, G. L. Conn, T. Brown and A. N. Lane. Nucleic Acids Res. 24 (19), 3693-3699, 1996.

Comparison of the thermodynamic stabilities and solution conformations of DNA.RNA hybrids containing purine- rich and pyrimidine-rich strands with DNA and RNA duplexes

J. I. Gyi, G. L. Conn, A. N. Lane and T. Brown. Biochemistry 35 (38), 12538-12548, 1996.

Comparison of the electrophoretic and hydrodynamic properties of DNA and RNA oligonucleotide duplexes

G. F. Bonifacio, T. Brown, G. L. Conn and A. N. Lane. Biophys. J. 73 (3), 1532-1538, 1997.

Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: Comparison with the DNA analogue d(CGCAAATTTGCG)2

M. R. Conte, G. L. Conn, T. Brown and A. N. Lane. Nucleic Acids Res. 25 (13), 2627-2634, 1997.

The dependence of DNase I activity on the conformation of oligodeoxynucleotides

D. H. Sutton, G. L. Conn, T. Brown and A. N. Lane. Biochem. J 321, 481-486, 1997.

Solution structures of DNA.RNA hybrids with purine- rich and pyrimidine-rich strands: Comparison with the homologous DNA and RNA duplexes

J. I. Gyi, A. N. Lane, G. L. Conn and T. Brown. Biochemistry 37 (1), 73-80, 1998.

The orientation and dynamics of the C2'-OH and hydration of RNA and DNA-RNA hybrids

J. I. Gyi, A. N. Lane, G. L. Conn and T. Brown. Nucleic Acids Res. 26 (13), 3104-3110, 1998.

The crystal structure of the RNA.DNA hybrid r(GAAGAGAAGC).d(GCTTCTCTTC) shows significant differences to that found in solution

G. L. Conn, T. Brown and G. A. Leonard. Nucleic Acids Res. 27 (2), 555-561, 1999.

The solution structure of a DNA.RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications

J. I. Gyi, D. Q. Gao, G. L. Conn, J. O. Trent, T. Brown and A. N. Lane. Nucleic Acids Res. 31 (10), 2683-2693, 2003.