Dr Simon Gerrard

Dr Simon Gerrard

Post-doctoral researcher (2010-2013)

Simon undertook his undergraduate studies in Chemistry at the University of Bristol (2003), including a year placement at GlaxoSmithKline. He moved to Southampton in 2004 to study for his PhD in the Brown group. His thesis was entitled “Novel nucleotide analogues for forming stable DNA triple helices”. In 2008, he took a post-doctoral position for Dr. Eugen Stulz in the same department, working on DNA-templated reactions and post-synthetic modification, then moved back to the Brown group in 2010 as a post-doctoral researcher. He is currently working in the field of DNA-based nanotechnology.

8 Papers

CG base pair recognition within DNA triple helices using N-methyl-3H-pyrrolo 2,3-d pyrimidin-2(7H)-one nucleoside analogues

S. R. Gerrard, N. Srinivasan, K. R. Fox and T. Brown. Nucleosides Nucleotides Nucl. Acids 26 (10-12), 1363-1367, 2007.

Potent Triple Helix Stabilization by 5',3'-Modified Triplex-Forming Oligonucleotides

N. Ben Gaied, Z. Y. Zhao, S. R. Gerrard, K. R. Fox and T. Brown. ChemBioChem 10 (11), 1839-1851, 2009.

CG base pair recognition within DNA triple helices by modified N-methylpyrrolo-dC nucleosides

S. R. Gerrard, M. M. Edrees, I. Bouamaied, K. R. Fox and T. Brown. Org. Biomol. Chem. 8 (22), 5087-5096, 2010.

Self-Assembled DNA-Based Fluorescence Waveguide with Selectable Output

J. K. Hannestad, S. R. Gerrard, T. Brown and B. Albinsson. Small 7 (22), 3178-3185, 2011.

Membrane Protrusion Coarsening and Nanotubulation within Giant Unilamellar Vesicles

I. Wegrzyn, G. D. M. Jeffries, B. Nagel, M. Katterle, S. R. Gerrard, T. Brown, O. Orwar, and A. Jesorka. J. Am. Chem. Soc. 133 (45), 18046-18049, 2011.

A New Modular Approach to Nanoassembly: Stable and Addressable DNA Nanoconstructs via Orthogonal Click Chemistries

S. R. Gerrard, C. Hardiman, M. Shelbourne, I. Nandhakumar, B. Norden and T. Brown. ACS Nano 6 (10), 9221-9228, 2012.

Triplex-mediated analysis of cytosine methylation at CpA sites in DNA

M. W. Johannsen, S. R. Gerrard, T. Melvin and T. Brown. Chem. Commun. 50, 551-553, 2014.

Reversible Ligation of Programmed DNA-Gold Nanoparticle Assemblies

P. K. Harimech, S. R. Gerrard, A. H. El-Sagheer, T. Brown and A. G. Kanaras. J. Am. Chem. Soc. 137 (29), 9242-9245, 2015.