Dr James Richardson
James finished his PhD in the Brown group in 2009, his thesis entitled Novel DNA probes for sensitive DNA detection, then remained in the group as a post-doctoral researcher. His main areas of interest were novel genetic analysis methods and the use of DNA in nano-engineering applications, with an interest in fluorescently labelled DNA and detection methodologies. After leaving the Brown Group in 2013 James joined Illumina and now works as a Senior Scientist in the Systems Integration department in Cambridge, UK.
12 Papers
SERS-Melting: A New Method for Discriminating Mutations in DNA Sequences
(46), 15589-15601, 2008.
J. Am. Chem. Soc. 130The Use of an Electroactive Marker as a SERS Label in an E-melting Mutation Discrimination Assay
(20), 2190-2197, 2009.
Electroanalysis 21End-capped HyBeacon probes for the analysis of human genetic polymorphisms related to warfarin metabolism
(12), 2728-2734, 2010.
Org. Biomol. Chem. 8Six-Colour HyBeacon Probes for Multiplex Genetic Analysis
(18), 2530-2533, 2010.
ChemBioChem 11Gauging the Flexibility of Fluorescent Markers for the Interpretation of Fluorescence Resonance Energy Transfer
(2), 279-285, 2011.
J. Am. Chem. Soc. 133Efficient reverse click labeling of azide oligonucleotides with multiple alkynyl Cy-Dyes applied to the synthesis of HyBeacon probes for genetic analysis
(3), 857-864, 2012.
Tetrahedron 68Real-Time Surface-Enhanced Raman Spectroscopy Monitoring of Surface pH during Electrochemical Melting of Double-Stranded DNA
(12), 5464-5470, 2012.
Langmuir 28A Label-Free, Electrochemical SERS Based Assay for the Detection of DNA Hybridization and the Discrimination of Mutations
(34), 14099-14107, 2012.
J. Am. Chem. Soc. 134Denaturation of dsDNA Immobilised at a Negatively Charged Gold Electrode is not caused by Electrostatic Repulsion
1625-1632, 2013.
Chem. Sci. 4,Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device
3626-3628, 2013.
Analyst 138,Rapid detection of diagnostic targets using isothermal amplification and HyBeacon probes – A homogenous system for sequence-specific detection
(2), 92-98, 2015.
Mol. Cell. Probes 29Synthesis and use of universal sequence probes in fluorogenic multi-strand hybridisation complexes for economical nucleic acid testing
(4), 228-236, 2015.
Mol. Cell. Probes 29